A multi-vehicle crash sent two people to the hospital Monday morning and closed eastbound Interstate 76 at E. 88th Ave., according to Colorado State Patrol (CSP). Watch Denver7 Traffic Expert Jayson Luber's full report in the vi deo player below. Multi-vehicle crash closes eastbound I-76 at E. 88th Ave. for morning commuteThe crash happened around 4:23 a.m. Monday, involving five vehicles and a semitruck hauling a trailer. Two people were taken to nearby hospitals, but CSP did not know the extent of their injuries, as of 5:41 a.m. Monday.There's no estimated time for reopening eastbound I-76, just west of E. 88th Ave., according to CSP. The crash had not been moved and the clenaup had not started, as of 6:22 a.m. Monday, according to Denver7 Traffic Expert Jayson Luber. Monday morning commuters are advised to find an alternative route. Luber recommended drivers use E. 74th Ave. to 72nd Ave., over to Highway 2 to get around the shutdown.CSP is leading the crash investigation, and has not yet determined a cause. ...read more read less