(KRON) -- One of the world's largest biotech companies is closing its only office in the Bay Area. Pfizer is shutting down its office space in South San Francisco this month, the company said in a statement. Pfizer said the departure of the 164,00 square-foot building is due to the office space be ing "underutilized." Employees based out of the five-story building on 181 Oyster Point Blvd. will transition to remote roles, the company added. The closure of the office will go into effect on April 30. "Pfizer continues to maintain a strong presence in California, including its facilities in San Diego," the statement said. Video above: Human metapneumovirus cases rising in the Bay Area ‘LinkedIn Speak’ translator goes viral amid layoffs across US Pfizer logo on glass office building facade with sky reflections, South San Francisco, California, October 16, 2025. (Photo by Smith Collection/Gado/Getty Images) Despite anti-Musk protests, Tesla remains best-selling car model in CA by a wide margin for 2025 It is unclear how many employees work out of the South San Francisco office. Pfizer said it is evaluating several options, which include subleasing the building. South San Francisco is considered one of the world's biggest conglomerates for biotechnology. The city dubs itself as "the birthplace of biotechnology," citing the founding of Genentech in 1976. Pfizer's global headquarters are located in New York City. The company became a household name during the COVID-19 pandemic as one of the three major vaccine providers, along with Moderna and Johnson Johnson. ...read more read less