Mining the dark transcriptome: Synthesizing the first potential drug molecules from long noncoding RNA
Mar 10, 2026
A team from University of Toronto Engineering is the first to synthesize long noncoding RNA (lncRNA) outside the cell—a new approach to drug discovery that has already yielded some promising anti-inflammatory molecules. The team was inspired by advances in the field of messenger RNA (mRNA) and pro
tein replacement therapies. They realized that a similar approach could be used to deliver lncRNA to the body, unlocking a potential new source of drugs. ...read more read less