Is Mifepristone significantly more dangerous than Tylenol?
Feb 06, 2026
No.
Both mifepristone and acetaminophen, the active ingredient in Tylenol, are widely used and studied drugs considered by experts to be safe and effective with hospitalization rates of less than 1%.
Though a higher percentage of milfepristone users require hospitalization than ac
etaminophen users, Sen. Lankford’s usage of this to claim that a prescription drug is more dangerous than an over-the-counter drug is unsound given the considerable differences between their purposes and the populations using them.
The fundamental differences between these drugs make any comparative claim regarding their safety “false, lacking in fair balance, or otherwise misleading,” according to FDA regulations for manufacturers.
Considering only causally related deaths, milfepristone has a mortality rate of 0.31 deaths per 100,000 abortions–less than half the overall abortion mortality rate of 0.7 and 28 times smaller than the pregnancy-related mortality rate of those who have a live-born infant.
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Oklahoma Watch partners with Gigafact to produce fact briefs — bite-sized fact checks of trending claims.
Sources
National Library of Medicine Acetaminophen ToxicitySupreme Court of the United States BRIEF OF OVER 300 REPRODUCTIVE HEALTH RESEARCHERS AS AMICI CURIAE IN SUPPORT OF PETITIONERSAmerican College of Obstetricians Gynecologists Mifepristone in the CourtsNational Library of Medicine Incidence of emergency department visits and complications after abortionCode of Federal Regulations § 202.1 Prescription-drug advertisements.Advancing New standards in Reproductive Understanding medication abortion complications as published by the FDA
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