Colts vs. 49ers MNF: CMC 1st TD Scorer on Bet365 (+275)
Dec 21, 2025
Monday Night Football concludes Week 16 with a high-stakes cross-conference battle as the San Francisco 49ers visit the Indianapolis Colts at Lucas Oil Stadium. bet365 is highlighting a premium player prop on 49ers star running back Christian McCaffrey to open the scoring at +275 odds.
https://www.syracuse.com/betting/2025/12/colts-vs-49ers-mnf-cmc-1st-td-scorer-on-bet365-275.html
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